All Diseases that Start with L (Rare, Deadly, and Many More!)

Welcome to our comprehensive exploration of diseases beginning with the letter “L”. In this extensive guide, we will delve into a wide range of conditions, including those affecting the blood, bones, eyes, and mental health, as well as lung, skin, and various diseases found in dogs and cats.

Additionally, we will discuss deadly, rare, autoimmune diseases, and various bacterial infections. Join us as we uncover the complexities and impacts of these conditions.

Top 30 Diseases that Start with L

Below are the 30 common diseases starting with the letter ‘L’.

• Leukemia: Cancer affecting blood and bone marrow.
• Lupus: Autoimmune disease affecting multiple organs.
• Lyme Disease: Bacterial infection from tick bites.
• Lymphoma: Cancer in the lymphatic system.
• Laryngitis: Inflammation of the voice box.
• Leptospirosis: Bacterial disease affecting animals and humans.
• Lichen Planus: Chronic skin rash condition.
• Lactose Intolerance: Inability to digest lactose.
• Legionnaires’ Disease: Severe form of pneumonia.
• Lipoma: Benign tumor of fatty tissue.
• Lichen Sclerosus: Chronic skin condition.
• Leishmaniasis: Parasitic infection from sandfly bites.
• Lateral Epicondylitis: Tennis elbow, tendon inflammation.
• Listeriosis: Infection caused by Listeria bacteria.
• Labyrinthitis: Inner ear infection causing vertigo.
• Lactation Mastitis: Infection in breast tissue.
• Laminitis: Hoof disease in horses.
• Leukoplakia: White patches inside the mouth.
• Lipedema: Abnormal fat distribution in legs.
• Loiasis: Parasitic infection by Loa loa worm.
• Loin Pain Hematuria Syndrome: Recurrent loin pain and blood in urine.
• Lumbar Spinal Stenosis: Narrowing of the spinal canal.
• Lumbar Disc Disease: Degeneration of spinal discs.
• Lumbar Spondylosis: Wear and tear of lumbar vertebrae.
• Lambert-Eaton Syndrome: Muscle weakness autoimmune disorder.
• Landau-Kleffner Syndrome: Rare childhood neurological disorder.
• Langerhans Cell Histiocytosis: Disorder involving excessive immune cells.
• Leukodystrophy: Progressive disorders affecting the brain, spinal cord, and nerves.
• Lewy Body Dementia: Type of progressive dementia.
• Lissencephaly: Rare brain formation disorder.

Also, Check:

Medical Terms That Start With L

Fitness Words That Start With L

After exploring rare and deadly diseases that start with ‘L’, our next sections will cover diseases categorized by their type, providing a more focused understanding of various health issues within specific bodily systems.

10 Rare Diseases Starting With L

1. Lambert-Eaton Myasthenic Syndrome (LEMS): Autoimmune disorder affecting nerve-muscle junctions.
2. Leigh’s Disease: Rare, inherited neurometabolic disorder.
3. Langerhans Cell Histiocytosis: Rare condition involving overproduction of Langerhans cells.
4. Lafora Disease: Progressive, inherited, neurodegenerative disorder.
5. Leber’s Hereditary Optic Neuropathy: Genetic disorder leading to sudden vision loss.
6. Lipodystrophy: Rare disorder involving abnormal fat distribution in the body.
7. Loeys-Dietz Syndrome: Genetic disorder affecting connective tissue.
8. Lowe Syndrome: Rare genetic condition affecting eyes, brain, and kidneys.
9. Lymphangioleiomyomatosis (LAM): Rare lung disease affecting women.
10. Leptomeningeal Carcinomatosis: Rare complication of cancer, affects meninges.

10 Deadly Diseases Starting With L

1. Lung Cancer: Leading cause of cancer-related deaths worldwide.
2. Leukemia: Various types of blood cancers that are often aggressive.
3. Lymphoma: Cancer that begins in the lymphatic system.
4. Liver Cancer: Primary or metastatic cancer in the liver.
5. Legionnaires’ Disease: Severe form of pneumonia caused by Legionella bacteria.
6. Leprosy (Hansen’s Disease): Chronic infectious disease causing severe, disfiguring skin sores and nerve damage.
7. Listeriosis: Serious infection caused by eating food contaminated with the bacterium Listeria monocytogenes.
8. Lyme Disease: Tick-borne illness that can lead to severe neurological and cardiac complications.
9. Loiasis: Parasitic infection that can cause severe complications if untreated.
10. Leptospirosis: Bacterial disease that affects humans and animals, can lead to kidney damage, meningitis, liver failure, and death.

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Other Diseases Beginning With L (Divided By Type)

Autoimmune Diseases That Start With L

• Lupus: Autoimmune disease affecting multiple organs.
• Linear IgA Disease: Autoimmune blistering disorder.
• Lichen Sclerosus: Chronic skin condition.
• Lambert-Eaton Myasthenic Syndrome: Rare autoimmune disorder.
• Lupus Nephritis: Kidney inflammation due to lupus.
• Lupus Pernio: Chronic skin manifestation of sarcoidosis.
• Lupoid Hepatitis: Chronic autoimmune liver disease.
• Lupus Erythematosus Tumidus: Rare form of cutaneous lupus.
• Lymphomatoid Papulosis: Rare skin disorder.
• Lymphocytic Colitis: Inflammation of the colon.
• Lichen Planopilaris: Scarring hair loss.
• Lichen Planus Pigmentosus: Pigmented skin disorder.
• Lichen Planus: Autoimmune skin rash.
• Linear Scleroderma: Autoimmune connective tissue disease.
• Lichen Nitidus: Tiny, shiny skin bumps.

Blood Diseases That Start With L

• Leukemia: Blood and bone marrow cancer.
• Lymphoma: Cancer in the lymphatic system.
• Leukocytosis: High white blood cell count.
• Leukopenia: Low white blood cell count.
• Lymphedema: Swelling due to lymphatic system blockage.
• Lymphocytopenia: Low level of lymphocytes.
• Langerhans Cell Histiocytosis: Disorder involving excessive immune cells.
• Lupus Anticoagulant Disorder: Increases blood clot risk.
• Lymphatic Leukemia: Type of blood cancer.
• Lymphocytic Leukemia: Chronic or acute blood cancer.
• Lymphangitis: Inflammation of lymphatic vessels.
• Lymphangioma: Malformation of the lymphatic system.
• Lymphangioleiomyomatosis: Rare lung disease.
• Lymphocytic Thyroiditis: Autoimmune thyroid inflammation.
• Lymphocytic Choriomeningitis: Viral infectious disease.

Bone Diseases That Start With L

• Leontiasis Ossea: Bone overgrowth facial disorder.
• Legg-Calve-Perthes Disease: Childhood hip disorder.
• Lumbar Spinal Stenosis: Narrowing of the spinal canal.
• Lumbar Disc Disease: Degeneration of spinal discs.
• Lumbar Spondylosis: Wear and tear of lumbar vertebrae.
• Langerhans Cell Histiocytosis: Disorder of immune cells.
• Limb-Girdle Muscular Dystrophy: Progressive muscle weakness.
• Limb Perthes Disease: Bone disorder in children.
• Langer’s Axillary Arch: Muscle variant affecting the shoulder.
• Lytic Bone Lesions: Bone destruction or weakening.
• Leiomyosarcoma of Bone: Rare bone cancer.
• Lumbar Radiculopathy: Nerve root disorder in the lower back.
• Lumbosacral Plexopathy: Nerve damage in the lower spine.
• Lumbosacral Spondylosis: Degenerative spine disorder.
• Lumbar Lordosis: Excessive inward curvature of the spine.

Eyes Diseases That Start With L

1. Lazy Eye (Amblyopia): Reduced vision in one eye.
2. Lattice Degeneration: Peripheral retina thinning.
3. Leber’s Congenital Amaurosis: Early childhood blindness.
4. Leber’s Hereditary Optic Neuropathy: Genetic vision loss.
5. Lagophthalmos: Inability to close eyelids fully.
6. Lacrimal System Disorders: Tear duct issues.
7. Lattice Dystrophy: Corneal disorder.
8. Lens Dislocation: Movement of the eye lens.
9. Low Vision: Reduced vision is not fixable by standard means.
10. Legal Blindness: Vision impairment meeting specific criteria.
11. Leukocoria: White pupil appearance.
12. Lymphoma of the Eye: Eye cancer.
13. Lacrimal Gland Tumor: Tumor in tear gland.
14. Lymphangioma of the Eye: Eye lymphatic system tumor.
15. Lisch Nodules: Iris pigmentation changes.

Ear Diseases That Start With L

1. Labyrinthitis: Inner ear infection causing vertigo.
2. Langerhans Cell Histiocytosis of the Ear: Ear canal tumor.
3. Lateral Sinus Thrombosis: Blood clot in the brain near the ear.
4. Lobar Pneumonia: Severe lung infection.
5. Lymphoma of the Ear: Cancer affecting ear lymphatics.
6. Labyrinthine Concussion: Inner ear damage due to head trauma.
7. Laryngeal Papillomatosis: Benign tumors in the throat.
8. Laryngospasm: Sudden closure of the vocal cords.
9. Laryngotracheobronchitis (Croup): Inflammation of upper airways.
10. Laryngeal Cancer: Cancer of the voice box.
11. Laryngitis: Inflammation of the voice box.
12. Laryngocele: Air-filled sac in the larynx.
13. Lateral Semicircular Canal BPPV: Benign paroxysmal positional vertigo.
14. Leukoplakia of the Ear: White patches in the ear.
15. Labyrinthine Fistula: Abnormal opening in the inner ear.

Hand Diseases That Start With L

1. Lateral Epicondylitis (Tennis Elbow): Tendon inflammation in the elbow.
2. Leprosy: Chronic infectious disease affecting skin and nerves.
3. Lupus: Autoimmune disease affecting the skin.
4. Lymphedema: Swelling due to lymphatic system blockage.
5. Ligamentous Laxity: Loose ligaments in hand.
6. Lacerations: Deep cuts or tears in the skin.
7. Leiomyoma: Benign soft tissue tumor.
8. Lichen Planus: Chronic skin rash.
9. Lichen Sclerosus: Chronic skin condition.
10. Limb-Girdle Muscular Dystrophy: Progressive muscle weakness.
11. Lipoma: Benign tumor of fatty tissue.
12. Limbic Encephalitis: Inflammation of the brain affecting hand coordination.
13. Lymphocytic Vasculitis: Inflammation of blood vessels in the hand.
14. Lymphangitis: Inflammation of lymphatic vessels in hand.
15. Langerhans Cell Histiocytosis of the Hand: Rare immune cell disorder affecting the hand.

Lung Diseases That Start With L

1. Lung Cancer: Malignant lung tumors.
2. Lobar Pneumonia: Severe lung infection.
3. Legionnaires’ Disease: Severe form of pneumonia.
4. Lymphangioleiomyomatosis: Rare lung disease.
5. Lung Abscess: Pus-filled cavity in the lung.
6. Laryngotracheobronchitis (Croup): Inflammation of upper airways.
7. Laryngeal Papillomatosis: Benign tumors in the throat.
8. Lymphangitis: Inflammation of lymphatic vessels in the lung.
9. Lung Fibrosis: Scarring of lung tissue.
10. Langerhans Cell Histiocytosis of the Lung: Lung disorder with excessive immune cells.
11. Lung Nodules: Small growths in the lung.
12. Lipoid Pneumonia: Lung inflammation due to lipid accumulation.
13. Lung Sarcoidosis: Inflammatory disease affecting the lungs.
14. Lymphoma of the Lung: Lung cancer affecting lymphatic tissue.
15. Lymphocytic Interstitial Pneumonitis: Inflammation of lung’s interstitial tissue.

Liver Lung Diseases That Start With L

1. Liver Cirrhosis: Long-term liver damage.
2. Liver Cancer: Malignant liver tumors.
3. Liver Abscess: Pus-filled cavity in the liver.
4. Liver Fibrosis: Scarring of liver tissue.
5. Leptospirosis: Bacterial disease affecting the liver and lungs.
6. Lymphoma of the Liver: Liver cancer affecting lymphatic tissue.
7. Langerhans Cell Histiocytosis of the Liver: Disorder with excessive immune cells in the liver.
8. Lipid Storage Diseases: Disorders causing fat accumulation in the liver.
9. Leishmaniasis: Parasitic infection affecting the liver.
10. Lyme Disease: Bacterial infection impacting the liver.
11. Lupoid Hepatitis: Chronic autoimmune liver disease.
12. Lymphocytic Cholangitis: Inflammation of bile ducts in the liver.
13. Lymphangioleiomyomatosis: Rare disease affecting lungs and liver.
14. Leptospirosis Pulmonary Hemorrhage Syndrome: Severe lung and liver infection.
15. Lymphedema of the Liver: Abnormal accumulation of lymphatic fluid in the liver.

Heart Diseases That Start With L

1. Left Ventricular Hypertrophy: Thickening of the heart’s left ventricle.
2. Long QT Syndrome: Heart rhythm disorder.
3. Lown-Ganong-Levine Syndrome: Fast heart rate syndrome.
4. Libman-Sacks Endocarditis: Heart valve disease.
5. Lymphocytic Myocarditis: Inflammation of heart muscle.
6. Leukemia Infiltrative Cardiomyopathy: Heart disease due to leukemia.
7. Lipid Storage Cardiomyopathy: Fat accumulation in the heart.
8. Left Atrial Myxoma: Benign tumor in the heart.
9. Lyme Carditis: Lyme disease affects the heart.
10. Lymphoma of the Heart: Cancer of the heart’s lymphatic tissue.
11. Leriche Syndrome: Blockage of the abdominal aorta.
12. Lung Hypertension: High blood pressure in lung arteries.
13. Left Ventricular Noncompaction: Rare heart muscle disorder.
14. Lupus Carditis: Lupus affecting the heart.
15. Lacunar Infarct: Small stroke affecting deep brain structures.

Mental Diseases That Start With L

1. Lewy Body Dementia: Type of progressive dementia.
2. Landau-Kleffner Syndrome: Rare childhood neurological disorder.
3. Logopenic Progressive Aphasia: Language impairment.
4. Late-Onset Schizophrenia: Schizophrenia starts in middle age.
5. Limbic Encephalitis: Brain inflammation affecting emotions.
6. Lacunar Amnesia: Memory loss due to stroke.
7. Leukodystrophy: Disorders affecting white matter in the brain.
8. Lissencephaly: Brain development disorder.
9. Lyme Neuroborreliosis: Lyme disease affecting the brain.
10. Lateral Medullary Syndrome: Stroke affecting the brainstem.
11. Lysosomal Storage Diseases: Disorders affecting cell function.
12. Lymphomatoid Granulomatosis: Brain disorder with immune cell proliferation.
13. Langerhans Cell Histiocytosis of the Brain: Brain disorder with excessive immune cells.
14. Leptomeningeal Carcinomatosis: Cancer spread to the meninges.
15. Lacunar Stroke: Small stroke in deep brain areas.

Skin Diseases That Start With L

1. Lupus: Autoimmune disease affecting the skin.
2. Lichen Planus: Chronic skin rash.
3. Lichen Sclerosus: Chronic skin condition.
4. Leishmaniasis: Parasitic skin infection.
5. Lyme Disease: Bacterial infection causing skin rash.
6. Lymphedema: Swelling due to lymphatic system blockage.
7. Lipoma: Benign tumor of fatty tissue.
8. Lymphangioma: Malformation of lymphatic vessels in the skin.
9. Lichen Simplex Chronicus: Thickened skin areas due to itching.
10. Lichen Nitidus: Tiny, shiny skin bumps.
11. Lichenoid Keratosis: Benign skin lesion.
12. Lichen Planopilaris: Scarring hair loss.
13. Leukemia Cutis: Leukemia cells in the skin.
14. Lamellar Ichthyosis: Skin scaling disorder.
15. Lymphoma of the Skin: Skin cancer affecting lymphatic tissue.

Bacterial Infection That Start With L

1. Lyme Disease: Bacterial infection from tick bites.
2. Legionnaires’ Disease: Severe form of pneumonia.
3. Listeriosis: Infection caused by Listeria bacteria.
4. Leptospirosis: Bacterial disease affecting animals and humans.
5. Lymphogranuloma Venereum: Sexually transmitted infection.
6. Leprosy (Hansen’s Disease): Chronic infectious disease.
7. Lactococcus Lactis Infection: Infection by dairy bacteria.
8. Leuconostoc Infection: Infection by bacteria in fermented foods.
9. Lactobacillus Infection: Infection by bacteria in probiotics.
10. Lyme Carditis: Lyme disease affects the heart.
11. Lemierre’s Syndrome: Rare bacterial infection.
12. Lactational Mastitis: Infection in breast tissue.
13. Laryngeal Tuberculosis: Tuberculosis affects the larynx.
14. Lymphadenitis: Infection of lymph nodes.
15. Listerial Meningitis: Brain infection by Listeria bacteria.

Dog Diseases That Start With L

1. Leptospirosis: Bacterial disease affecting kidneys and liver.
2. Lyme Disease: Tick-borne bacterial infection.
3. Lymphoma: Cancer affecting the lymphatic system.
4. Leishmaniasis: Parasitic infection from sandfly bites.
5. Lipoma: Benign tumor of fatty tissue.
6. Laryngeal Paralysis: Loss of larynx function.
7. Luxating Patella: Dislocation of the kneecap.
8. Liver Shunt: Abnormal blood flow around the liver.
9. Lymphedema: Swelling due to lymphatic system blockage.
10. Lupus: Autoimmune disease affecting multiple organs.
11. Lick Granuloma: Skin lesion from excessive licking.
12. Leukemia: Blood and bone marrow cancer.
13. Lameness: General term for difficulty walking.
14. Liver Cancer: Malignant liver tumors.
15. Lumbar Spinal Stenosis: Narrowing of the spinal canal.

Cat Diseases That Start With L

1. Leukemia (Feline Leukemia Virus): Viral infection in cats.
2. Lymphoma: Cancer in the lymphatic system.
3. Lyme Disease: Tick-borne bacterial infection.
4. Lipoma: Benign tumor of fatty tissue.
5. Laryngeal Paralysis: Loss of larynx function.
6. Luxating Patella: Kneecap dislocation.
7. Liver Shunt: Abnormal blood flow around the liver.
8. Lymphedema: Swelling due to lymphatic system blockage.
9. Lupus: Autoimmune disease affecting the skin.
10. Lymphocytic Plasmacytic Stomatitis: Inflammatory oral disease.
11. Larva Migrans: Infection by roundworm larvae.
12. Leishmaniasis: Parasitic infection from sandfly bites.
13. Liver Lipidosis (Fatty Liver Disease): Excessive fat in the liver.
14. Lenticular Sclerosis: Age-related eye condition.
15. Lameness: General term for difficulty walking.